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For one, it makes a robust clinical trial logistically tricky, said Christopher Milne, past director of research at the Tufts Center for the Study of Drug Development

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Sankey Diagrams Supplydemand flows and channel volume distribution

If semaglutide (single agonist) is first generation, and tirzepatide and mazdutide (dual agonists) are second generation, then retatrutide (triple agonist) is the beginning of the third generation

The method is homogeneous, making it easy to automate by standard robotic manipulation of microwell plates