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formal analyses of antibody formation or systemic immune responses after topical or parenteral administration are lacking

Nutrients (2024) 16:1468

Although the present study demonstrates histological and biochemical protection, functional assessments such as limb perfusion, contractile strength, and locomotor activity were not performed

Armstrong et al

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Even when supplements are helpful, improvements in symptoms like cycle regularity, mood, and hot flashes often take several weeks or longer to become noticeable