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Nature 2011 472(7341):40 - 41 M

In the SURPASS clinical trial program for type 2 diabetes (Mounjaro), constipation was reported in approximately 12-17% of patients across the 5 mg, 10 mg, and 15 mg weekly doses, with higher rates generally observed at higher doses

But as the number of people taking these drugs grows, physicians and researchers are learning about unanticipated health benefits for conditions where treatments have been limited, such as addiction, heart failure, and kidney disease

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In 2023, when Ozempic went mainstream, more than 4,000 semaglutide ad campaigns flooded the internet