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Glycoengineering has been successfully used to increase exposure and pharmacodynamics of darbepoetin, a hyperglycosylated analogue of erythropoietin 35 and our glycosylated GLP-1 analogue peptide fusion variant Ab#2_GLP1 W25N V27S showed indeed in vivo stability improvement (Fig

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Symptoms of restless legs syndrome tend to worsen at night because dopamine follows a circadian rhythm and reaches its lowest point during the evening

Dipeptidyl peptidase IV (DDP IV) in NASH patients