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As the condition progresses, the pain becomes persistent and increasingly severe, lasting for several days

One of the strongest studies supporting the need for early, comprehensive, long-term specialty treatment is that of Kessing et al

However, too long a delay in bringing these drugs to an employer-sponsored plan could mean a disadvantage in recruitment and retention, as well as a decline in productivity and overall health of population

Most people find that symptoms become manageable or disappear entirely by week four, though a small percentage continue experiencing mild side effects for longer

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