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So youre potentially adding a drug that slows gastric emptying to a body that already has a predisposition to gastric dysmotility
The TRIUMPH-4 trial reported percent body weight changes of -26.4% at the 9mg dose and -28.7% at the 12mg dose, compared to just -2.1% with placebo
This is a very interesting hypothesis, but we lack data of comparison between mothers of living DS individuals and women who experience loss of trisomy 21 pregnancies in order to evaluate differences in the frequency of polymorphisms of folate pathway genes between the two groups, or the preferential transmission of certain alleles to those DS embryos that reach the birth with respect to those that die in utero , so that the question is still unsolved
If youre currently pregnant, your doctor will want to provide extra monitoringprobably some additional ultrasounds and possibly genetic screening if that gives you peace of mind
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Key takeaways Wegovy is a once-weekly semaglutide injection that should be stored between 36 F and 86 F
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