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A patient with certain FTO or MC4R variants may face steeper adherence challenges or require higher tirzepatide doses, but genetics represent only one factor among many influencing weight loss success

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McIlwain CC et al

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Its use in non-clinical experimental designs supports investigations into mitochondrial function, lipid-associated signaling mechanisms, and cofactor-driven enzymatic activity, contributing to broader research into metabolic regulation and cellular bioenergetics

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