One recent paper found nearly 39,000 cardiovascular events were avoided when patients had access to obesity treatment, along with improvements in chronic kidney and liver diseases
A 10-year longitudinal follow-up of a retrospective cohort comprising 159 patients with PCOS treated with metformin reported that the total testosterone and androstenedione decreased to 15.4 47.9% and 11.3 46.4% within first year, with further decrease in total testosterone and androstenedione to 37.8 61.8 and 24.8 40.5% at the fifth year of the follow-up (22)
1I, YTHDF1 KO significantly enhanced the sensitivity of G401 cells to doxorubicin, even at a relatively low concentration (0.1 M)
It is entirely understandable to feel frustrated if existing treatments have not met your expectations
GLP-1RAs alleviate liver injury by inhibiting hepatocyte apoptosis and promoting the TFEB-dependent transcription of lysosome-related genes, which stimulates hepatocyte autophagy to prevent lipid accumulation (Elsiad et al., 2025
Altered composition of the gut microbiome in patients with drug-resistant epilepsy