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Central Nervous System Agents in Medicinal Chemistry

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Eng has recounted in interviews that the VA saw no commercial value in the discovery, so he filed the patent himself before licensing it forward, later reimbursed by Amylin for the cost

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All participants have severe obesity (a BMI of 35 or more) as well as at least one cardiovascular disease

For a compound to gain FDA approval, it must go through extensive, multi-phase clinical trials in humans to prove both safety and efficacy for a specific condition