However, the long-term safety, metabolic clearance, and potential cumulative toxicity of these synthetic materials require further systematic evaluation
Graves' orbitopathy results in profound changes in tear composition: a study of plasminogen activator inhibitor-1 and seven cytokines
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Because of their geometric structure that is similar to DNA, such new 2D nanomaterials can effectively accumulate in the kidneys, improve the side effects of conventional antioxidant drugs, such as N-acetylcysteine and amifostine, and avoid rapid metabolism, low utilization and low efficacy while having no significant toxicity for treating AKI (Figure 6B) ( 3 C2-PVP nanosheets (TPNSs) also has biodegradability triggered by enzymes/ROS
10.1021/bi011459o Biochemistry 104 PompellaA.CortiA.PaolicchiA.GiommarelliC.ZuninoF