In the placebo-controlled analyses for change in HbA 1c and change in body weight, we conducted a post hoc sensitivity analysis excluding one trial with a short duration (12 weeks) [18] and one trial that recruited participants on background insulin therapy [19]
Gastrointestinal side effects including nausea, vomiting, diarrhea, and constipation affect 3050% of patients during the first weeks
Our Heartburn Relief Products Antacids vs PEPCID COMPLETE vs PPIs Lifestyle Tips for Managing Heartburn on GLP-1s Some people taking GLP1 medicines may notice gastrointestinal reactions such as heartburn, fullness, or indigestion
However, the evidence for causality remains limited, and the findings across studies have rather conflicting outcomes
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Another notable effect is that they also slow digestion and suppress appetite