doi: 10.3389/fmed.2023.1124275 Received 14 December 2022 Accepted 27 February 2023 Published 22 March 2023 Volume 10 - 2023 Edited by Ana Sandoval-Rodriguez, University of Guadalajara, Mexico Reviewed by Angelo Armandi, University of Turin, Italy
5-HTP has been administered to thousands of human subjects in hundreds of studies since the 1950s (PubMed)
BioMed Research International, 2015 , 648108
Its levels decrease due to various factors, the primary one is aging
Then maintenance treatment can begin
However, researchers estimate that the lethal dose of GHK-Cu would be about 330 mg/kg of body weight, which is over 300 times larger than its known effective dose