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The addition of glucagon receptor activation is the primary pharmacological difference

Different death stimuli evoke apoptosis via multiple pathways in retinal pigment epithelial cells

Most gastrointestinal side effects such as bloating and gas are mild and self-limiting, typically resolving within days to weeks as the gut microbiome adjusts to the introduced bacterial strains

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Cohort 1 (n=7 males, 9 females) was used for Experiment 1 and cohort 2 (n=7 males, 3 females) was used in Experiments 2-4