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However, metabolic response depends on individual insulin sensitivity baseline, genetic factors, and overall metabolic health status, which vary considerably across PCOS presentations

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Many people find it helpful to have a baseline measurement of their TSH, Free T4, and Free T3 before starting a medication that significantly impacts metabolism

This review article discusses the potential antidepressant effects of GLP-1RAs, especially in the context of their action on the processes related to neuroprotection, inflammation, stress response, energy metabolism, gut-brain crosstalk and the stability of the gut microbiota