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DOI: 10.1016/j.tem.2017.02.004
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Individuals with B12 deficiency, which can occur due to dietary restrictions (e.g., vegan or vegetarian diets), gastrointestinal disorders affecting absorption, older age, or certain medical conditions that interfere with B12 absorption
No receptor-mediated adverse events (e.g., cardiovascular effects, endocrine disruption) have been reported, consistent with NNMT's limited expression outside metabolic tissues
B12 supports metabolism and helps convert fat and carbohydrates into energy, making it easier to lose weight when combined with healthy eating and exercise
PMC: PMC11226645
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