Pica behavior is a validated endpoint to assess the ability of a compound to induce nausea/malaise in non-vomiting species, as mouse, based on the monitoring of non-nutritive (kaolin) food intake, as an index of gastrointestinal discomfort 43,44
What Are Melanotan and MT2 Peptides
It is caused by reduced saliva production from GLP-1 receptor effects on salivary glands and from reduced chewing stimulation
( Epub 2018 Oct 21 PMID: 30345551 ) Besemer F, Verschoor AJ, Diamant M, Hoogma RP (2012) Vesiculopustular dermatosis: an uncommon side-effect of liraglutide
Patients exploring related treatment options may also want to review information on Mounjaro for prescription weight management or Wegovy patient experiences as part of broader research into GLP-1 treatment options
Dose capacity limitations and the need for repeated application limit the practicality of most therapeutic peptides