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People taking metformin, the common diabetes drug, are known to develop B12 deficiency as well, and people who avoid animal products can be deficient

Specifically, nerve damage caused by vitamin B12 most often affects the extremities (hands and feet)

Elevated levels of these markers are a much more sensitive sign of a true deficiency than the standard B12 test alone

Nevertheless, to our knowledge, the effect of oral cobalamin treatment in patients presenting with severe neurological manifestations has not yet been adequately documented

they simply help deliver them efficiently

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