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The REDEFINE 1 data was limited by a titration schedule that may have been too aggressive roughly half of participants reached the full 2.4/2.4 mg dose

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Dietary management and microbiota modulation have been clinically recommended for IBD treatment according to clinical guidelines

Additionally, these medications significantly slow down digestion

Retatrutide Drawbacks and Limitations Like any new treatment, Retatrutide may come with some potential downsides and unknowns: 1

Your PlexusDx provider will guide the transition timing to avoid gaps in appetite control and to prevent unwanted metabolic rebound during the switch