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We analyzed the ChIP-seq data reported recently 26 and identified a super-enhancer encompassing the mouse Cyp8b1 (Supplementary Fig

SURMOUNT-1 (Jastreboff et al., NEJM 2022) reported 22.5% body weight loss at 72 weeks at the 15 mg dose

GLP-1 agonists appear to enhance serotonin activity in certain brain pathways

If no: 0% coverage probability for weight-loss indication If yes: proceed to question 5 Question 5: Have you completed required step therapy

Continuous glucose monitoring-measured glucose levels during oral glucose tolerance testing in pregnancy

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