Let me just say, I'm beyond happy I gave this supplement a chance before resorting to more extreme measures (and I would totally recommend that you do too)
Every item below is independently verifiable - don't take anyone's word for any of them, including this article
A research of 163 patients with idiopathic/hereditable pulmonary hypertension (PH), congenital heart disease-associated PH, and chronic thromboembolic PH examined plasma TMAO levels as a possible biomarker in PH
None of these have been answered with rigorous human data
Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials
This work is illuminating neurobiological explanations for hunger and satiety, pleasure and rewardas well as why these sensations so critical to survival might get dysregulated, causing compulsive behaviors and addictive patterns