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Abstract Glutathione is a tripeptide synthesized at cytosolic level, that exists in cells in a reduced form (thiol-reduced-GSH-) and in an oxidized form (disulfide-oxidized)

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The STEP 1 trial showed average weight loss of 14.9% over 68 weeks, with around half of participants losing 15% or more of their body weight

Relevant clinical diseases Neurodegenerative diseases Generally, neurodegenerative diseases (NDDs) exhibit multiple and common pathological effects, including defects in mitochondria, protein quality control, and the autophagic-lysosomal network, which lead to the aggregation and accumulation of misfolded proteins [173, 174]

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