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Because GLP-1 receptor agonist medications slow gastric emptying, some patients may retain significant amounts of food or fluid in the stomach even after standard preoperative fasting periods

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ClinicalTrials.gov registrations: STEP 1 NCT03548935, STEP 4 NCT03548987, SUSTAIN-6 NCT01720446, SELECT NCT03574597

CDCA-mediated FXR stimulation occurs in ileal enterocytes and hepatocytes and mediates the expression of fibroblast growth factor 15/19 (FGF 15/19) and small heterodimer protein (SHP) (Sonne, 2021)

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