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In 2005, exenatide was approved as a kind of GLP-1 receptor agonists (GLP-1RAs) for the clinical treatment of type 2 diabetes mellitus (T2DM) as the first international incretin drug [6]

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doi:10.1111/jsr.14054

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Therefore, our results suggest the unique importance of understanding the metabolomic problems that occur early in the diseased motor cortex, and encourages for the development of novel therapeutic strategies by reestablishing the perturbed NAD + levels in the brain

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Nat Commun 15 , 6941 (2024)

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