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by Kanthi Bommareddy, MD

NEJM, 2021 Jastreboff AM et al

GLP-1s seem to offer some benefit in brain health, says McIntyre

Keeping the Weight Off After Menopause Weight Loss Because appetite returns if a GLP-1 is reduced or stopped, the maintenance plan is as important as the weight loss itself, and it should be built from the start rather than scrambled together at the end

Choose injectable BPC-157 if: Your target is a tendon, ligament, joint, or muscle injury You need systemic anti-inflammatory or tissue repair effects Speed and reliability of delivery matter You are working within a structured peptide therapy protocol with a licensed provider Choose oral BPC-157 if: Your primary concern is gut health leaky gut, IBD, IBS, gastric ulcers You want high local GI concentrations, not systemic distribution You prefer non-invasive administration for long-term or maintenance use You are combining BPC-157 with another systemic peptide therapy Consider nasal delivery only if: Neurological applications are the clinical focus A licensed provider explicitly recommends it based on your presentation Injection is contraindicated and oral delivery is insufficient Do not choose a delivery method based on convenience alone

Limited insurance coverage and recent shortages only complicate access