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It helps lower insulin levels, leading to weight loss and a reduction in androgen-related symptoms

Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007

CRP, C-reactive Protein

They also had increased oxidative stress, demonstrated by higher levels of glutathione peroxidase (GPx), lipid peroxidation products (MDA), protein oxidation, and superoxide anions in both cortex and hippocampus in this group

Human serum was from the author Briony Forbes and provided with informed consent

Previous research has shown that GPx1 is an effective antioxidant enzyme that cannot be replaced by any other selenoprotein to protect against generalized oxidative stress [74,75,76]