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Nature Reviews
Such differing characteristics result from the continuous mutations malignancies undergo, resulting in differing biochemical and genetic characteristics, even in the same tumor (Higashiyama 2012
Nutrients 12:114
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Co-enzyme B12 also interacts with the enzyme methionine synthase (5-methyltetrahydrofolate-homocysteine methyltransferase), required for the conversion of homocysteine to methionine, which is essential for folic acid metabolism and the formation of thymine, which is a component of DNA
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