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However, effects on advanced fibrosis remain under investigation, with phase 2 trials of semaglutide showing MASH resolution without confirmed fibrosis improvement

Tesofensine and semaglutide have both shown promise for weight loss in clinical trials, but they vary in their mechanisms of action and approved uses

A.GaoH.LuoL.et al (2023)

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In major studies, participants using semaglutide lost an average of 15% of their body weight over 68 weeks

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