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Under the first phase of the ongoing two part study, the drug demonstrated "statistically significant improvement in liver fibrosis and resolution of steatohepatitis compared to placebo." In August 2025, the company received final approval to market the therapy for the additional indication in the US, followed by a conditional approval in Canada in December

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7.2 episodes per 100 patient-years of exposure, respectively)

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Entinostat, an HDAC inhibitor, has also been reported to be able to activate the Wnt signal 15,31