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If dosing is too high or continuous without breaks, the body will downregulate its own endogenous pathways and could become dependent or have blunted natural hormone production

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NAC enhances extracellular cysteine and by using transport channels increases intracellular cysteine (Franco and Cidlowski, 2009

Studies show that sublingual glutathione works better than regular oral forms, with improved GSH/GSSG ratios showing reduced oxidative stress

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