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Second, the TTH sample ( n = 19) may have been underpowered to detect subtle GSH alterations, and the conclusion that GSH reduction is specific to migraine should be interpreted cautiously pending replication with larger TTH cohorts that account for potential heterogeneity (e.g., episodic frequency, coexisting conditions)

In EAT the drug reduced FABP4 and perilipin 1 ( PLIN1 ), but not ADIPOQ expression and on SAT it reduced PPAR coactivator 1-alpha ( PGC1) expression

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The answer is: it depends on the research goal