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doi: 10.1089/ars.2012.5052 29 HernndezJ

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A study demonstrated that hyperglycemia induces excess ROS production from mononuclear cells, which subsequently triggers the release of tumor necrosis factor- (TNF-) (105)

Mutation of Glu170 decreased the reciprocal Dalziel coefficient 1/ 1 by up to 56% whereas 1/ 2 remained constant (Fig