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Dose may be increased in increments of 2.5 mg every 4 weeks as needed

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During these critical periods, the body performs essential maintenance functions including tissue repair, immune system strengthening, and memory consolidation

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465 The anterior cingulate cortex, essential for emotional pain processing, shows increased blood flow in patients with PDPN, a hyperperfusion state that normalizes following duloxetine treatment

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This depends entirely on the treatment goal and formulation

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DISCLOSURES Cindy Wassef, Radhika Shah, Mahin Alamgir, Samantha Ouellette, and Giulia Frias have no conflicts of interest to disclose

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