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Using semaglutide past the recommended period can lower its effectiveness and may pose health risks
Your BMI is 30 or higher
For information on what happens when weight loss stalls at any dose, see not losing weight on semaglutide
[1] [2] However, stopping the medication suddenly does have important metabolic consequences that patients should understand
Discordance between randomised controlled trials and observational studies
Drug: Trevogrumab (REGN-1033), anti-myostatin monoclonal antibody Developer: Regeneron Pharmaceuticals Trial: COURAGE (Phase 2), 599 patients randomized Lead investigator: Julio Rosenstock, M.D., UT Southwestern / Velocity Clinical Research Best result: 92.6% of weight loss from fat (triplet combo) Timeline: Phase 3 expected 2027
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