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Semaglutide is generally well-tolerated with side effects that are predominantly gastrointestinal, mild-to-moderate in severity, and transient in nature, occurring most frequently during dose escalation

Sandra LL, Talia WO, Carol P, Rosalinda S, Paulina R, Angelica C, Sonia V

CYP24A1, a gene that provides instructions for making the enzyme 24-hydroxylase, is involved in the catabolism of both 25(OH)VD 3 and 1,25(OH) 2 D 3, thereby limiting vitamin D receptor (VDR)/1,25(OH) 2 D 3 signaling 14

Thats why the body produces antioxidants like GSH to help keep free radical levels in check and prevent damage to the body

there are reports that ALA can lower circulating thyroid hormone (T3/T4) or reduce the efficacy of thyroid medications like levothyroxine, which means thyroid function should be monitored if ALA is used concurrently

The dose is adjusted as needed to get the best results