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Simoni, R

"ICER has a budget impact threshold that estimates whether the uptake of a drug can lead to a budget impact concern," he said

5 Besides, the reported increase in mean arterial pressure following direct infusion of hydrogen peroxide (H 2 O 2 ) into the renal medulla of normotensive rats suggests that the accumulated H 2 O 2 in renal medulla might have a hypertensive consequence