glp-1 birth defects Taking GLP-1s during the first trimester of pregnancy does not appear to substantially increase the risk of adverse outcomes Navigating GLP-1 and Pregnancy: Insights,

Gigliotti et al., 2025): Adapt to changing hunger cues and find a sustainable eating rhythm Manage GI symptoms through pacing, hydration, and fiber adjustments Understand the importance of resistance exercise and protein intake to preserve muscle mass and prevent excessive metabolic slowdown Stay nourished while balancing medication side effects and real-life routines Regular follow-up is key

how reimbursement dynamics will shape penetration in the US and the EU5 (France, Germany, Italy, Spain and the UK)

A 2023 randomized controlled trial published in the BMJ (N=410) found that spironolactone 50 to 100 mg/day produced a significantly greater reduction in acne lesion count versus placebo at 24 weeks, with a mean difference of 12.0 fewer inflammatory lesions (95% CI 7.6 to 16.4, P 90% (albumin) | Low

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In this months newsletter, Clinical Research Associate Joe Bonner, PhD will briefly review how this can happen and the importance of tracking skeletal muscle mass during weight loss

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