This phenomenon appears to be multifactorial, driven by increased awareness of androgen deficiency syndromes, the expanding off-label prescription of testosterone preparations, and the widespread non-medical use of anabolicandrogenic steroids (AAS) to enhance physical performance and appearance
Moreover, radical-scavenging antioxidants such as Astragenol, Acteoside, and Edaravone have demonstrated neuroprotective effects in NDDs, primarily by neutralizing ROS, promoting GSH synthesis, and maintaining GPX4 activity to alleviate neuronal ferroptosis (Xiao et al., 2025
Competition and expansion to improve public reimbursement There is already strong reimbursement coverage of GLP-1s for T2D across US federal, state and commercial payors
This might be because of their price point, side effects or the act of self-injecting medication
For understanding side effect differences, the semaglutide versus tirzepatide side effects comparison provides clarity
Its a science-backed therapy designed to be part of a personalized, long-term wellness plan