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A large network meta-analysis comparing weight loss and side effects found more treatment stops at the highest doses, especially due to nausea and vomiting, for both drugs, with slightly higher rates at maximum doses

Side effects include nausea, vomiting, and diarrhea

Wang IY et al

while significant pharmacokinetic interactions with psychiatric medications are not generally expected, GLP-1 agonists may affect absorption of some oral medications due to delayed gastric emptying Discuss realistic expectations regarding weight loss and diabetes control to avoid disappointment that might affect mood Ensure adequate support systems are in place, including regular contact with healthcare providers Discuss pregnancy plans as these medications are not recommended during pregnancy or breastfeeding

Glutathione peroxidase-1 expression enhances recovery of human breast carcinoma cells from hyperoxic cell cycle arrest

As a practicing nurse, over time the administration of injections to my patients and clients has become routine and somewhat second nature