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25 have shown that inhibition of the GSH redox cycle enhances acetaminophen cytotoxicity in cultured rat hepatocytes
There is no published long-term human safety data, no completed RCT, and the most-cited theoretical concern remains angiogenesis in the context of undiagnosed cancer
Active cancer or history of malignancy Pregnancy or breastfeeding Known peptide allergies Athletes subject to anti-doping testing (WADA prohibited) Raynauds disease or phenomenon Cold urticaria (hives from cold) Uncontrolled hypertension Peripheral vascular disease Open wounds (for local application) Pregnancy Cardiovascular conditions Diabetes (especially with neuropathy) Current infections Immunosuppression Blood clotting disorders Quality control issues represent perhaps the greatest practical risk with BPC-157
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First, using strong acids to stop the enzymatic reaction is problematic
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