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Decades of research have highlighted the clinical demerits of abnormally high body weight (BW), with BMIs exceeding 30 kg/m 2 and 40 kg/m 2 correlated with decreased life expectancies of three and 10 years, respectively

In human cosmetic split-face studies (n values typically 20 to 93 participants), measurable skin density and fine-line improvements appear from week 4, with most outcomes reported at 8 to 12 weeks of daily topical use

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2020;45(Suppl 1):4360