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Central Nervous System Research Applications Standard rodent CNS protocols include middle cerebral artery occlusion (stroke model), controlled cortical impact (traumatic brain injury), cuprizone feeding (demyelination), and spinal cord compression

The injections are relatively painless, with most patients experiencing only a slight pinch at the injection site

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Alcohol is not strictly contraindicated with either compound, but it undermines the protocol in multiple ways

Mild soreness at the injection site may arise but usually resolves within a few hours