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Due to tirzepatide's pharmacokinetic profile (peak concentration at approximately 24-48 hours and half-life of about 5 days), symptoms may persist for several days following a double dose, with effects potentially lasting longer than with shorter-acting GLP-1 receptor agonists
Pharmacologic GLP-1 RAs are synthetic analogs designed to resist degradation by dipeptidyl peptidase-4 (DPP-4), thereby prolonging their half-life
There are three main types of diabetes covered in this factsheet
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Interruption anywhere along the cycle could be responsible ( Figure 23 )
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