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Additionally, leptin exerts influence over the expression of substances like dynorphin and brain-derived neurotrophic factor, both directly and indirectly through neuronal projections originating from the ARC and other hypothalamic regions

Several factors may account for these findings

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& Conforti, L

Its protease-resistant structure makes it a stable reference compound for melanocortin receptor pharmacology

(2015) A randomised controlled trial comparing duloxetine and acetyl L-carnitine in fibromyalgic patients: preliminary data