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Moreover, research suggests that it may play a role in treating moderate to severe OCD ( Likewise, an animal study suggested that NAC may minimize the adverse effects of schizophrenia, such as social withdrawal, apathy, and reduced attention spans ( NAC may also have applications in managing substance use disorders

Broader gene expression and signaling effects have been summarized in experimental models

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Niacinamide does not cause the dramatic flush of niacin, so titration to mitigate flushing is usually not necessary