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Week-by-Week Protocol Week 1: First Reta Dose Inject your starting dose (see table above) Note: food noise may temporarily return This is normalthe GIP ratio is different in retatrutide Week 2: Assessment If no new side effects: Bump by 0.5mg (if starting dose was under 2mg) Bump by 1mg (if starting dose was 2mg+) If experiencing glucagon-related effects (jitteriness, different hunger pattern, mild nausea): Stay at current dose another week Weeks 36: Find Your Effective Dose Continue titrating every 12 weeks Target: find the dose where satiety + energy feel stable Most people land between 36mg weekly for maintenance Week 6+: Maintenance Lock in your effective dose Adjust only if plateau lasts 3+ weeks What to Expect During Transition The First Two Weeks Food noise may return temporarily

Brands may consider reducing drink serving sizes that align with consumer preferences both during and after their weight loss journey

Some people may also need additional time or dosage adjustments before seeing meaningful results

In the process, we aim to help patients better understand how insurance works so they can advocate for themselves with confidence, now and in the future

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Weight-loss medications included in membership If eligible, Oral Weight-Loss Medication Kits including metformin, bupropion, and/or naltrexone come complimentary with your membership, delivered in one easy kit, straight to your door