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Association between sitagliptin use and heart failure hospitalization and related outcomes in type 2 diabetes mellitus: secondary analysis of a randomized clinical trial

I., Cuzi, S., Brajsa, K., Mildner, B., Bokuli, A., Situm, K., Perovi, D., Glojnari, I., & Parnham, M

S., Ramalho, R

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No genotoxicity, mutagenicity, or organ-specific toxicity was reported at the doses tested in the preclinical safety evaluation

Proponents argue this maintains more stable tissue levels, though others find once-daily dosing equally effective with better compliance