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Red flag symptoms that require evaluation include: Hair loss accompanied by scalp changes such as redness, scaling, itching, or pain Patchy hair loss in distinct circular areas (suggesting alopecia areata) Hair breakage rather than shedding from the root Loss of eyebrow or body hair in addition to scalp hair Associated symptoms such as fatigue, cold intolerance, or unexplained weight changes beyond expected GLP-1 effects These features may indicate alternative or additional diagnoses requiring specific treatment

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When they do occur, they are usually mild (involving the skin only)

doi: 10.1007/s00125-022-05715-4 131 Snchez-GarridoMABrandtSJClemmensenCMllerTDDiMarchiRDTschpMHet al

This can include drug metabolites, heavy metals, pesticides/herbicides, xenoestrogens like BPA, alcohol, and other toxic chemicals