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Piening A, Ebert E, Gottlieb C, Khojandi N, Kuehm LM, Hoft SG, et al

In rats undergoing Roux-en-Y gastric bypass (RYGB), transcript levels of Tlr4, Myd88, Cd14, and downstream pro-inflammatory cytokines including Il1b, Il6, Il18, and Tnfa were significantly reduced in the hypothalamus, suggesting a procedure-specific attenuation of TLR4 signaling

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Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay IA-O, McGowan BM, Rosenstock J, Tran MTD, Wadden TA, Wharton S, Yokote K, Zeuthen N, Kushner RF