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Mitochondria, which are structures within the cells of the RPE that act as energy powerhouses, are particularly susceptible to ROS-induced damage [17]

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With intramuscular (IM) injections the standard treatment for severe deficiency or malabsorption conditions like pernicious anaemiaserum B12 levels rise rapidly, typically reaching therapeutic ranges within 2448 hours after the first injection

This is sound guidance for most formulations - but the reason behind the vitamin C caution is worth understanding, because it doesn't apply equally to all forms

Undissolved particles should not be injected

320 , H2080H2100 (2021)