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Activation of the Nrf2-ARE pathway attenuates hyperglycemia-mediated injuries in mouse podocytes

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Nat Rev Endocrinol 8(12):728742

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Stage 1 includes individuals with higher risk of developing dysglycaemia (defined based on validated country-specific risk scores than those with stage 0 or normal -cell function, whose high insulin resistance would be compensated by increased insulin production and glucose remains near normal despite gradual minimal decline in -cell function or mass

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